Factors Predicting Microinvasion in Ductal Carcinoma in situ

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Factors predicting microinvasion in Ductal Carcinoma in situ.

BACKGROUND Whether sentinel lymph node biopsy (SLNB) should be performed in patients with pure ductal carcinoma in situ (DCIS) of the breast has been a question of debate over the last decade. The aim of this study was to identify factors associated with microinvasive disease and determine the criteria for performing SLNB in patients with DCIS. MATERIALS AND METHODS 125 patients with DCIS who...

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Different distribution of breast ductal carcinoma in situ, ductal carcinoma in situ with microinvasion, and invasion breast cancer

BACKGROUND Breast ductal cancer in situ (DCIS) can recur or progress to invasive ductal cancer (IDC), and the interim stage include DCIS with microinvasion (DCIS-Mi). In this article, we attempt to study the study the differences of clinicopathological features, imaging data, and immunohistochemical-based subtypes among DCIS, DCIS-Mi, and IDC. METHODS In this retrospective study, we attempt t...

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Predictors of microinvasion and its prognostic role in ductal carcinoma in situ.

BACKGROUND We sought to determine factors predicting microinvasion and the prognostic role it plays in patients with ductal carcinoma in situ (DCIS). METHODS A retrospective cohort study of 205 consecutive patients presenting to the Yale Breast Center, New Haven, CT, was performed. RESULTS Fifty-one (24.9%) patients had microinvasion on pathology. Patients with microinvasion had larger area...

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Biologic behavior and long-term outcomes of breast ductal carcinoma in situ with microinvasion

BACKGROUND Ductal carcinoma in situ with microinvasion (DCIS-Mi) generally has favorable prognosis, but the long-term outcomes of DCIS-Mi and the biologic evolution from ductal carcinoma in situ (DCIS), DCIS-Mi, to DCIS with T1a breast cancer (DCIS-T1a) has not been specified. The aim of our study was to explore the biological and prognostic features of DCIS-Mi, compared with pure DCIS and DCIS...

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Ductal carcinoma in situ.

Management of ductal carcinoma in situ (DCIS) has evolved from radical surgery to the option of a more minimally invasive approach. Data show that breast conservation surgery performed with administration of radiotherapy, like mastectomy, is feasible and safe. Because efforts to find a safe group for elimination of radiotherapy have resulted in data that conflict, radiotherapy still remains sta...

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ژورنال

عنوان ژورنال: Asian Pacific Journal of Cancer Prevention

سال: 2014

ISSN: 1513-7368

DOI: 10.7314/apjcp.2014.15.1.55